It sounds like there's something you're doing that's generating a ton stuff to compute. Do you have an autospawner or soul shard out of control? Maybe spawning mobs into your wiring? Or some machine is producing a product in a loop? Are you flying over a large new area, requiring the computer to generate a bunch of chunks? One thing to check: hit f3, and see how many chunk updates are occurring. Normal range should be 0 into the hundreds, and it should probably vary a fair amount, often dropping to 0.